Contraindications of OPV and adverse events

OPV is a very safe vaccine and there is no contraindication to prevent giving it. Serious adverse reactions to OPV are very rare: acute flaccid paralysis has been reported in approximately one child in every 1–10 million children who have been vaccinated with OPV.

Summary of oral polio vaccine (OPV) immunization characteristics.

Type of vaccine Live-attenuated antiviral vaccine
Number of doses Four (referred to as OPV0, OPV1, OPV2 and OPV3), plus campaign doses
Schedule At birth, 6, 10 and 14 weeks
Additional dose If the child spits or vomits after OPV, repeat the dose immediately; if the child has diarrhoea, give a fifth dose at least 4 weeks after the scheduled fourth dose
Contraindications None
Adverse events Very rarely AFP; refer immediately to a higher health facility
Special precautions None
Dosage 2 drops
Administration route Into the mouth (oral)
Storage Store between +2°C and +8°C (may be frozen for long-term storage)

What should you do if a baby vomits immediately after being given the oral polio vaccine?

Show answer

You should repeat the dose immediately; it is quite safe to give the baby an extra dose of OPV.

Last modified: Saturday, 24 May 2014, 12:27 PM